![]() ![]() Clinical manifestation dramatically improved following parenteral administration of atropine sulphate. Most human cases have highlighted the reversible nature of this poisoning.2 Clinical manifestation in previous reported cases includes vomiting, miosis, mydriasis, bradycardia, hypotension, hyperglycemia and CNS stimulation or depression and respiratory failure.3 Our patient presented with miosis and irritability. Since very few human cases have been reported, our knowledge in Amitraz poisoning is mainly based on animal studies. Ultrasonography incidentaly showed thickened edematous gall bladder and colitis. Renal and hepatic parameters were normal. Haemoglobin was 7.7 gm/dl, Total leukocyte count was 9,200/cumm, differential leukocyte count was polymorphs 78% and lymphocytes 20%, platelet count was 1.9/cumm lakhs, retic count was 2.1%, malarial parasite was negative, prothrombin time was normal, serum sodium was 138 mEq/L, serum potassium was 4 mEq/L. Patient was discharged on 4th day after slow tapering of atropine. He become completely conscious and oriented after around 40 hours. Six hours following hospital stay, patient slowly regained consciousness. Other supportive measures like gastric lavage, proton pump inhibitors, iv fluids and hydrocortisone were given. Patient was started on atropine sulphate and we titrated the dose of atropine sulphate till the signs of atropinisation, following that patient was started on maintenance dose of atropine. On examination, pulse was feeble and blood pressure was non-recordable, patient was drowsy and irritable with bilateral constricted pupil. Patient had consumed 4 ml Amitraz around 1 hour back following which he developed irritability. With history of suicidal Amitraz ingestion and was successfully treatedĪ 28 year old male was brought in an agitated state with alleged history of Amitraz ingestion. Neurological, respiratory and cardiovascular systems. Intoxication cases may have clinical manifestations involving Literature and most of the reported cases are from Turkey. Very less cases of intoxication have been reported in It is used for the treatment of demodicosis Here we present such a case treated successfully withĪmitraz is an alpha-2 receptor agonist that belongs to theįormamidine group of drugs. Very few cases have been reported with Amitraz as a suicidalĪgent from India.
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